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However, our approach is a significant advance on these earlier methods, for the following reasons: snap-freezing of samples followed by reaction with IAM-TPP/IAM enables us to trap and stablise all reactive sulfur species simultaneously through their nucleophilic reactions to generate stable products, rather than leaving labile moieties that may be modified during sample workup

During the metabolomic in silico analysis, certain compounds posed a challenge for the software due to their inherent tendency to produce fragments very easily

The FDA review is, in many ways, a public catch-up to a standard we already hold ourselves to

Behavioral and Neural Biology, 54(2), 110114

[22] Peter Malliaras et al., Patellar Tendinopathy: Clinical Diagnosis, Load Management, and Advice for Challenging Case Presentations, The Journal of orthopaedic and sports physical therapy 45, no

IMP also induces the expression of TGF-1 and activates phosphorylation of Smad-3 and Erk1/2, contributing to inflammatory damage in MCs and renal fibrosis [80]